SPRITAM is manufactured with US-sourced levetiracetam by Aprecia Pharmaceuticals, LLC in Blue Ash, Ohio USA. The manufacturing facility is the first and only in the world to receive FDA authorization to produce a three-dimensionally printed pharmaceutical product for commercial sale in the United States.

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Manufactured Using 3D Printing

ZipDose® Technology is the first and only drug-formulation platform that uses 3D printing (3DP).1. Data on file. Aprecia Pharmaceuticals, LLC.This proprietary process does not rely on compression forces, punches, or dies. Instead, 3DP binds layers of powdered medication together with an aqueous fluid to manufacture pharmaceutical products that are solid, yet highly porous. The porous design helps medication disintegrate rapidly in the mouth when taken with a sip of liquid.11. Data on file. Aprecia Pharmaceuticals, LLC.

A powder blend is deposited as a single layer

The binding fluid is applied to bind the particles

This process is repeated several times to manufacture orodispersible dosage forms

Creating Medication Using 3D Printing

Take a closer look at the 3DP manufacturing process.